Motif ID: NANOG{mouse}.p2

Z-value: 1.356


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox



Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_200395741 2.455 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_+_159817752 0.802 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr22_-_28992787 0.775 NM_020530
OSM
oncostatin M
chr7_+_6380614 0.763 NM_006908
NM_018890
RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr1_-_200396328 0.758 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_-_45339605 0.731 NM_182493
MYLK3
myosin light chain kinase 3
chr9_+_134275431 0.673 NM_207417
C9orf171
chromosome 9 open reading frame 171
chr1_+_159899528 0.664 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr12_+_7348194 0.650 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr18_-_21924531 0.645 NM_001007559
NM_005637
SS18

synovial sarcoma translocation, chromosome 18

chr14_+_19681734 0.635 NM_001004724
OR4N5
olfactory receptor, family 4, subfamily N, member 5
chr16_+_29582480 0.628 SPN
sialophorin
chr19_-_43608641 0.618 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr7_+_143646150 0.616 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr1_-_172103745 0.610 GAS5
growth arrest-specific 5 (non-protein coding)
chrX_+_44588192 0.603 NM_022076
DUSP21
dual specificity phosphatase 21
chr17_-_31441390 0.560 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chrX_+_133952633 0.546 NM_001163438
LOC644538
hypothetical protein LOC644538
chr22_+_35777561 0.538 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr8_+_28614929 0.531 EXTL3
exostoses (multiple)-like 3
chr2_-_183610992 0.526 NCKAP1
NCK-associated protein 1
chr2_+_171381317 0.523 NM_000817
NM_013445
GAD1

glutamate decarboxylase 1 (brain, 67kDa)

chr5_+_156625629 0.518 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chrX_-_119898692 0.496 NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080141
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A11
CT47A10
CT47A9
CT47A8
CT47A6
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A6
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr3_-_52542748 0.492 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chrX_-_134798808 0.481 NM_001017438
CT45A3
CT45A4
CT45A5
CT45A6
CT45A1
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A5
cancer/testis antigen family 45, member A6
cancer/testis antigen family 45, member A1
chr6_-_161614962 0.478 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr19_+_876984 0.466 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr1_+_172104115 0.465 NM_001122770
NM_032522
ZBTB37

zinc finger and BTB domain containing 37

chr11_-_66961709 0.464 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr16_-_3025542 0.463 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr4_+_154345039 0.461 NM_015271
TRIM2
tripartite motif containing 2
chr1_+_35507145 0.457 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr1_+_35507197 0.440 ZMYM4
zinc finger, MYM-type 4
chr19_+_56319948 0.433 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr4_+_39376058 0.423 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr11_+_6854431 0.415 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr8_+_28615062 0.414 NM_001440
EXTL3
exostoses (multiple)-like 3
chr3_-_42427026 0.413 NM_144634
LYZL4
lysozyme-like 4
chr13_+_107720206 0.407 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr6_-_20320607 0.401 NM_001080480
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr19_+_4920123 0.401 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr8_-_9045548 0.400 NM_024607
PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chrX_-_133758812 0.391 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr7_+_150013716 0.384 NM_015660
GIMAP2
GTPase, IMAP family member 2
chrX_+_138440560 0.383 NM_000133
F9
coagulation factor IX
chr10_-_79356285 0.379 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr7_-_30032649 0.373 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr7_-_75876830 0.368 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr6_-_32206029 0.367 NM_022110
FKBPL
FK506 binding protein like
chr8_-_103493637 0.359 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr10_+_72245730 0.354 SGPL1
sphingosine-1-phosphate lyase 1
chrX_+_134674850 0.351 NM_001017417
CT45A3
CT45A4
CT45A1
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A1
chr11_-_57883117 0.347 NM_001005489
OR5B17
olfactory receptor, family 5, subfamily B, member 17
chr13_+_107720475 0.344 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr10_+_95362334 0.339 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr10_+_18729518 0.338 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_143523582 0.335 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr3_+_38363292 0.331 XYLB
xylulokinase homolog (H. influenzae)
chr19_-_13074973 0.331 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr22_+_17539198 0.328


chr5_-_138767654 0.325 NM_194296
SPATA24
spermatogenesis associated 24
chr16_+_2959467 0.324 PAQR4
progestin and adipoQ receptor family member IV
chr19_+_15058790 0.323 NM_001004713
OR1I1
olfactory receptor, family 1, subfamily I, member 1
chr14_+_28306633 0.321 FOXG1
forkhead box G1
chr16_+_8675904 0.320 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr9_+_139566129 0.320 NM_032477
MRPL41
mitochondrial ribosomal protein L41
chr3_+_38363299 0.311 XYLB
xylulokinase homolog (H. influenzae)
chrX_-_48713194 0.308 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_+_203503214 0.307 TMCC2
transmembrane and coiled-coil domain family 2
chrX_+_55132221 0.306 NM_207339
PAGE2
P antigen family, member 2 (prostate associated)
chr19_+_4920126 0.300 KDM4B
lysine (K)-specific demethylase 4B
chr6_-_30760413 0.297 KIAA1949
KIAA1949
chr7_+_94953148 0.289 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr10_+_97879457 0.287 NM_014803
ZNF518A
zinc finger protein 518A
chr12_-_55696542 0.287 NM_001178054
NM_013251
TAC3

tachykinin 3

chr19_-_13074513 0.286 LYL1
lymphoblastic leukemia derived sequence 1
chr13_+_107719977 0.283 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr8_-_144583718 0.282 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr17_-_36528113 0.281 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr6_+_31647854 0.281 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr10_+_80942362 0.277 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr1_-_27113018 0.273 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr1_-_148508030 0.273 NM_001077628
NM_016022
APH1A

anterior pharynx defective 1 homolog A (C. elegans)

chr11_+_817584 0.271 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr3_+_38363226 0.268 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chr13_+_107720561 0.267 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr3_+_123256902 0.265 NM_175862
CD86
CD86 molecule
chr14_-_106084085 0.260 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_125070613 0.259 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr9_-_125070675 0.259 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr22_+_39817733 0.258 EP300
E1A binding protein p300
chr1_+_157676135 0.256 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr1_+_36121400 0.256 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr19_-_18058632 0.254 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr3_-_52235218 0.252 NM_017442
TLR9
toll-like receptor 9
chr1_-_25164061 0.252 NM_001031680
RUNX3
runt-related transcription factor 3
chr2_-_73313823 0.250 NM_032319
C2orf7
chromosome 2 open reading frame 7
chr1_+_200191241 0.249 NM_006335
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr1_+_109884016 0.247 NM_031936
GPR61
G protein-coupled receptor 61
chr12_-_121780835 0.245 NM_032554
GPR81
G protein-coupled receptor 81
chr1_+_47037256 0.243 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr6_+_88089008 0.243 NM_001042493
NM_020425
C6orf162

chromosome 6 open reading frame 162

chr19_+_6838576 0.243 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr8_+_66744659 0.241 NM_001145838
MTFR1
mitochondrial fission regulator 1
chr2_+_131950135 0.240 NM_080386
TUBA3D
tubulin, alpha 3d
chr20_+_3775421 0.238 NM_020746
MAVS
mitochondrial antiviral signaling protein
chr1_-_204011166 0.237 NM_001135662
NM_001135663
NM_001135664
NM_003929
RAB7L1



RAB7, member RAS oncogene family-like 1



chr6_-_31740645 0.236 NM_033177
GPANK1
G patch domain and ankyrin repeats 1
chr1_-_224143389 0.236 NM_020997
LEFTY1
left-right determination factor 1
chr14_+_75907442 0.235 NM_004452
ESRRB
estrogen-related receptor beta
chr11_-_128217550 0.234 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_-_133256097 0.231 NCKAP5
NCK-associated protein 5
chr4_+_166468266 0.231 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr12_-_121753795 0.227 NM_177551
GPR109A
G protein-coupled receptor 109A
chr10_+_97879645 0.226 ZNF518A
zinc finger protein 518A
chr2_-_96351345 0.224


chr2_+_68815416 0.223 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr20_+_18742369 0.223 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr20_+_57942213 0.221 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr3_+_15444056 0.218 NM_033083
EAF1
ELL associated factor 1
chr8_+_124849860 0.216 FAM91A1
family with sequence similarity 91, member A1
chr20_-_57942063 0.211 SYCP2
synaptonemal complex protein 2
chr16_+_31401939 0.210 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr4_+_123380569 0.210 KIAA1109
KIAA1109
chr19_+_40337480 0.209 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr10_-_73167586 0.208 NM_001168390
C10orf105
chromosome 10 open reading frame 105
chr16_+_6009095 0.208 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chrX_+_14457340 0.204 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr10_-_104587069 0.203 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr3_+_2908920 0.200 NM_175613
CNTN4
contactin 4
chr6_-_139350710 0.198 REPS1
RALBP1 associated Eps domain containing 1
chr6_+_26195426 0.198 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr9_+_33667169 0.198


chr1_+_62674562 0.197 NM_001017415
NM_001017416
USP1

ubiquitin specific peptidase 1

chr19_+_3129735 0.197 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr1_-_145712107 0.195 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr10_-_1024261 0.193


chr16_+_56259657 0.193 NM_170776
GPR97
G protein-coupled receptor 97
chr8_+_22078622 0.192 BMP1
bone morphogenetic protein 1
chr17_-_46140015 0.191 NM_052855
ANKRD40
ankyrin repeat domain 40
chr19_-_13074669 0.191 LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_229181240 0.190 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr19_-_44034797 0.190 NM_001005335
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr8_-_103494073 0.189 UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr5_+_68549317 0.184 NM_033281
MRPS36
mitochondrial ribosomal protein S36
chr2_+_157822355 0.184 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr22_+_25347927 0.183 NM_001886
CRYBA4
crystallin, beta A4
chr11_-_6418705 0.181 NM_000613
HPX
hemopexin
chr16_+_8714326 0.180 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr10_-_1024280 0.178 LOC100288619
hypothetical LOC100288619
chr8_+_124849923 0.178 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr6_-_31741369 0.178 GPANK1
G patch domain and ankyrin repeats 1
chrX_-_118711350 0.178 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr13_-_52211836 0.178 LECT1
leukocyte cell derived chemotaxin 1
chr1_+_20338405 0.176 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr6_-_33494042 0.175 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr1_-_157313179 0.175 NM_004833
AIM2
absent in melanoma 2
chr19_+_47073029 0.174 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chrX_+_70438352 0.172 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr19_-_18515376 0.171 NM_012181
FKBP8
FK506 binding protein 8, 38kDa
chr6_+_34312625 0.171 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr7_-_72894774 0.171 NM_152559
WBSCR27
Williams Beuren syndrome chromosome region 27
chr15_-_47125788 0.170 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr1_-_153560532 0.169 NM_001039517
C1orf104
chromosome 1 open reading frame 104
chr22_-_37878394 0.169 NM_175709
CBX7
chromobox homolog 7
chr6_+_34312554 0.167 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr1_-_229181229 0.167 TTC13
tetratricopeptide repeat domain 13
chrX_+_55118228 0.167 NM_001015038
PAGE2B
P antigen family, member 2B
chr10_-_71753684 0.166 LRRC20
leucine rich repeat containing 20
chr5_-_137502975 0.166 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr1_-_148507779 0.165 APH1A
anterior pharynx defective 1 homolog A (C. elegans)
chr11_-_84311867 0.164 DLG2
discs, large homolog 2 (Drosophila)
chr19_-_56612653 0.164 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr7_-_106088565 0.163 NM_175884
FLJ36031
hypothetical protein FLJ36031
chrX_+_48427137 0.162 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_-_119927878 0.162 NM_173571
NM_001080137
NM_001080138
NM_001080139
NM_001080141
NM_001080142
NM_001080143
NM_001080144
NM_001080145
NM_001080146
CT47A11
CT47A10
CT47A9
CT47A8
CT47A6
CT47A5
CT47A4
CT47A3
CT47A2
CT47A1
cancer/testis antigen family 47, member A11
cancer/testis antigen family 47, member A10
cancer/testis antigen family 47, member A9
cancer/testis antigen family 47, member A8
cancer/testis antigen family 47, member A6
cancer/testis antigen family 47, member A5
cancer/testis antigen family 47, member A4
cancer/testis antigen family 47, member A3
cancer/testis antigen family 47, member A2
cancer/testis antigen family 47, member A1
chr17_-_59131194 0.161 LIMD2
LIM domain containing 2
chr22_-_22426551 0.160 NM_013378
VPREB3
pre-B lymphocyte 3
chr6_+_41304039 0.158 NM_198153
TREML4
triggering receptor expressed on myeloid cells-like 4
chr19_-_18515280 0.158 FKBP8
FK506 binding protein 8, 38kDa
chr8_+_42871176 0.158 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr16_+_2959342 0.157 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr2_+_218790109 0.156 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr1_+_154386358 0.156 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_157441133 0.156 NM_002036
DARC
Duffy blood group, chemokine receptor
chr11_+_120966280 0.156 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr14_+_102659464 0.156 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr19_+_2200112 0.154 NM_000479
AMH
anti-Mullerian hormone
chr2_+_203587807 0.154 NM_001114132
NBEAL1
neurobeachin-like 1
chr17_+_45527507 0.153 NM_002611
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr19_+_55073192 0.153 TBC1D17
TBC1 domain family, member 17
chr7_+_148475373 0.152 NM_170686
ZNF398
zinc finger protein 398
chr10_+_92912676 0.151 PCGF5
polycomb group ring finger 5
chr7_+_86812864 0.150 NM_001143935
NM_021151
CROT

carnitine O-octanoyltransferase

chr10_+_129735796 0.149 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_-_15349086 0.149 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr10_-_48010879 0.149 NM_002900
RBP3
retinol binding protein 3, interstitial
chr6_-_33493898 0.149 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr4_-_82345224 0.149 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.13 1.11e-02 GO:0007606 sensory perception of chemical stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.66 1.19e-03 GO:0004888 transmembrane receptor activity
1.56 1.27e-03 GO:0004872 receptor activity
1.77 5.52e-03 GO:0004930 G-protein coupled receptor activity
2.18 6.17e-03 GO:0004984 olfactory receptor activity
1.44 1.04e-02 GO:0004871 signal transducer activity
1.44 1.04e-02 GO:0060089 molecular transducer activity